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Download Drug Discovery: A History by Walter Sneader PDF

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By Walter Sneader

Written by means of a number one authority with a superb attractiveness and talent for writing a great narrative, Drug Discovery: A History is a much cry from easily a listing of chemical buildings.

This full of life new textual content considers the origins, improvement and heritage of medications that generate excessive media curiosity and feature a tremendous social and financial effect on society.

Set inside a large historic, social and cultural context, it offers multiplied insurance of pre-twentieth century medications, the massive advances made within the 20th century and the most recent advancements in drug learn.

Hallmark features:

  • Up-to-the-minute info in drug research
  • Vignettes of designated and strange info, and anecdotes
  • Discusses drug prototypes from all sources
  • More accomplished than different volumes on historical past of drug discovery

From the reviews:

"...an very good bibliographic source for these drawn to the historical past papers that function the basis for discovery of particular drug entities." magazine OF clinical CHEMISTRY, June 2006

"...a very entire evaluation of drug improvement. it may be at the shelf on any aspiring pharmacist, medicinal chemist, or individual attracted to the background of healing agents." magazine OF CHEMICAL schooling, February 2006

"...a very readable and heavily researched book..." CHEMISTRY & undefined, October 2005

Content:
Chapter 1 advent (pages 1–7):
Chapter 2 The Prehistoric interval (pages 6–11):
Chapter three Pre?Hellenic Civilisations (pages 12–17):
Chapter four Greece and Rome (pages 18–23):
Chapter five The Arab international (pages 24–31):
Chapter 6 Herbals (pages 32–40):
Chapter 7 Chemical medicinal drugs (pages 41–73):
Chapter eight Systematic drugs (pages 74–87):
Chapter nine Alkaloids (pages 88–105):
Chapter 10 Non?Alkaloidal Plant items (pages 106–114):
Chapter eleven Plant Product Analogues and Compounds Derived from Them (pages 115–150):
Chapter 12 The Origins of Hormone treatment (pages 151–154):
Chapter thirteen Neurohormones (pages 155–163):
Chapter 14 Peptide Hormones (pages 164–172):
Chapter 15 intercourse Hormones (pages 173–178):
Chapter sixteen Adrenal Cortex Hormones (pages 179–184):
Chapter 17 Prostaglandins (pages 185–187):
Chapter 18 Hormone Analogues (pages 188–225):
Chapter 19 supplements (pages 226–247):
Chapter 20 Antimetabolites (pages 248–268):
Chapter 21 Blood and organic items (pages 269–286):
Chapter 22 Antibiotics (pages 287–318):
Chapter 23 Antibiotic Analogues (pages 319–340):
Chapter 24 Pharmacodynamic brokers from Micro?Organisms (pages 341–348):
Chapter 25 Analogues of Pharmacodynamic brokers from Fungi (pages 349–354):
Chapter 26 the 1st man made medicinal drugs and Their Analogues (pages 355–374):
Chapter 27 medicines Originating from the Screening of Dyes (pages 375–402):
Chapter 28 medicines Originating from the Screening of natural chemical substances (pages 403–431):
Chapter 29 medications came across via Serendipitous Observations regarding people (pages 432–437):
Chapter 30 medications came upon via Serendipity within the Laboratory (pages 438–445):
Chapter 31 Concluding feedback (pages 446–447):

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Extra info for Drug Discovery: A History

Sample text

Riddle, Dioscorides on Pharmacy and Medicine, History of Science Series, No. 3. Austin: University of Texas Press; 1986. R. Gunther, The Greek Herbal of Dioscorides. ; 1959. htm Claudius Galenus, Opera Omnia, Hildesheim: Georg Olms Verlag; 2001. _______________________________________________________________________________________________________ CHAPTER ___________________________ 5 The Arab World The origins of Baghdad as the leading medical centre of the Muslim world in the ninth century are obscure, but it has often been claimed that in the year 765 Jirjis Bakhtyishu’, the head of a prominent medical school in Jundishapur (situated about 300 miles to the south-east of Baghdad), was summoned to the capital to treat Caliph al-Mansur for dyspepsia.

An English translation was printed in 1577 under the title Joyfull Newes Out of the Newe Founde Worlde. The complete work mentioned products such as balsam, china root, coca, guaiac, jalap, passion flower, guava, sarsaparilla, sunflower and tobacco, all of which soon appeared in the premises of apothecaries throughout the continent. Monardes was not the first to recommend guaic, a resin exuded from the heartwood of the small West Indian tree known now as Guaiacum officinale L. This was already in wide use 34 _________________________________________________________________________________________ Legacy of the Past against syphilis, then generally believed to have been imported into Spain on the return from the West Indies of those who sailed with Columbus.

As Arab physicians were strongly influenced by Galen, it might seem surprising to encounter such detailed information on the preparation and uses of minerals, about which Galen was certainly far from enthusiastic. 2 In India, links between medicine and alchemy had been developed in the fourth and fifth centuries and subsequently many Arab physicians dabbled in it, thereby ensuring a continuing supply of minerals for medicinal purposes. Troubled by a hot, dry climate and frequent sandstorms, their patients often developed eye and skin diseases for which the application of soothing ointments containing sulfur and mercury became almost routine.

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