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By G.M. Thomas

Even if experimental and scientific melanoma learn have to be heavily associated, advances on the uncomplicated point usually stay distant from clinical software. This magazine works to speed up the interpretation of experimental effects to the hospital. In each one factor, findings from easy examine are built-in with present theoretical wisdom and mentioned by way of their relevance to the detection and therapy of melanoma. major scientific reports from melanoma centres worldwide are integrated, supplemented through occasional case reviews and reports. This name examines evolving methods to enhance results and reduce toxicities in radiation treatment.

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Extra resources for Evolving Approaches to Improve Outcomes and Minimize Toxicities in Radiation Therapy (Oncology)

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20 Gatenby RA, Kessler HB, Rosenblum JS, Coia LR, Moldofsky PJ, Hartz WH, Broder GJ: Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy. Int J Radiat Oncol Biol Phys 1988;14:831–838. 21 Nordsmark M, Overgaard M, Overgaard J: Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck. Radiother Oncol 1996; 41:31–39. 22 Höckel M, Vaupel P: Biological consequences of tumor hypoxia. Semin Oncol 2001;28(suppl 8):36–41.

16 Hanks GE, Lu J, Machtay M, Venkatesan V, Pinover W, Byhardt R, Rosenthal SA: RTOG Protocol 92-02: a phase III trial of the use of long-term androgen suppression following neoadjuvant hormonal cytoreduction and radiotherapy in locally advanced carcinoma of the prostate [abstract]. Proc Am Soc Clin Oncol 2000;19:1284a. 17 Grogan M, Thomas GM, Melamed I, Wong FLW, Pearcey RG, Joseph PK, Portelance L, Crook J, Jones KD: The importance of hemoglobin levels during radiotherapy for carcinoma of the cervix.

8 Whitney CW, Sause W, Bundy BN, Malfetano JH, Hannigan EV, Fowler WC, Clarke-Pearson DL, Liao SY: Randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stage IIBIVA carcinoma of the cervix with negative para-aortic lymph nodes: a Gynecologic Oncology Group and Southwest Oncology Group study. J Clin Oncol 1999;17:1339–1348. 9 Morris M, Eifel PJ, Lu J, Grigsby PW, Levenback C, Stevens RE, Rotman M, Gershenson DM, Mutch DG: Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer.

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