Download Methods of Hyperthermia Control by Michel Gautherie, T.C. Cetas, Thaddeus V. Samulski, Peter PDF
By Michel Gautherie, T.C. Cetas, Thaddeus V. Samulski, Peter Fessenden, Jean C. Bolomey, M.S. Hawley, Maurice Chive
The huge, immense capability that hyperthermia has for reaping benefits sufferers with melanoma is impressively indicated by way of organic reviews, either in vitro and in vivo, and by way of comparative scientific reports every time the warmth has been appro priate to the dimensions of the tumor. yet hyperthermia, as with every different technologically dependent scientific tactics, calls for an intensive strengthen ment of subtle instrumentation and strategies to supply regimen scientific profit. We most likely erred in beginning scientific trials so quickly. We had was hoping that via exhibiting the scientific advantages on a few superficial tumors quick, monetary aid will be encouraged for the mandatory technolog ical advancements. regrettably, treating superficial affliction correctly was once tougher than we had meant and neighborhood remedies have been much less profitable than we had needed. The actual purposes are transparent and have been obvious from the start, even if in our enthusiasm we neglected them. conditions are varied now. we need to deal with quite a lot of tumors in numerous websites, however the structures and methods required are just on hand in a number of laboratories and clinics the place they nonetheless are present process refinement.
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Extra resources for Methods of Hyperthermia Control
In this example, a temperature profile has been measured in normal canine brain tissue close to an energized interstitial microwave antenna . The profiles are measured using two different temperature probes. The discrepancy between the respective profiles is the result of the difference in the thermal conductivity of the probe shaft. One is a quartz glass optical probe, the other a stainless steel needle with an embedded thermistor sensor. Because of the large temperature field curvature near the interstitial device, temperature averaging or smearing associated with the metal needle results in a substantially lower maximum temperature as well as spatial distortion.
Rev Sci Inst 54:1687 -1692 60. Wise JA, Soulen Jr RJ (1986) "Thermometer calibration", a model for state calibration laboratories. (NBS Monograph 174) US Government Printing Office, Washington DC 61. Lyons BE, Samulski TV, Britt RH (1985) Temperature measurements in high thermal gradients. I. The effects of conduction. Int J Radiat Oncol Bioi Phys 11 :951- 962 62. Samulski TV, Lyons BE, Britt RH (1985) Temperature measurements in high thermal gradients: II. Analysis of conduction effects. Int J Radiat Oncol Bioi Phys 11:963-971 63.
Multichannels (16 + ) systems 5. Cost-effective 1. Small signal levels 2. High thermal conduction 3. EM interference and artifact 4. US viscous artifact 31 (single-point calibration) 3. Low thermal conductivity 4. d. 5. Multichannel (8) system 2. US absorption artifact Acknowledgment. The authors wish to acknowledge and thank Jeanne Forest and Gerard Honore for their assistance in preparing this manuscript. Thermistor thermometry Advantages (+) Disadvantages (- ) 1. High accuracy and resolution 2.