Download Nuclear Oncology by Cumali Aktolun, Stanley Goldsmith MD PDF
By Cumali Aktolun, Stanley Goldsmith MD
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Extra info for Nuclear Oncology
Phase I trial results of iodine-131-labeled anti-tenascin monoclonal antibody 81C6 treatment of patients with newly diagnosed malignant gliomas. J Clin Oncol. 2000;18:3862–3872. 106. Riva P, Franceschi G, Riva N, et al. Role of nuclear medicine in the treatment of malignant gliomas: The locoregional radioimmunotherapy approach. Eur J Nucl Med. 2000;27:601–609. 107. Goetz C, Riva P, Poepperl G, et al. Locoregional radioimmunotherapy in selected patients with malignant glioma: Experiences, side effects and survival times.
2000;41:447–452. 55. Maldona A, Santos M, Rodriquez S, et al. The role of FDG PET in resolving diagnostic doubt: Recurrence versus radionecrosis in brain tumors [abstract 124]. Mol Imag Biol. 2002;4:S32. 56. Thompson TP, Lunsford LD, Kondziolka D. Distinguishing recurrent tumor and radiation necrosis with PET versus stereotactic biopsy. Stereotact Funct Neurosurg. 1999;73:9–14. 57. Ricci PE, Karis JP, Heiserman JE, et al. Differentiation recurrent tumor from radiation necrosis; time for re-evaluation of PET?
90Y versus 131 I) used for labeling the MoAb. Adjusting the amount of radioactivity that will be used for labeling the MoAb according to the tumor size and/or surgical resection cavity size is another topic that requires further investigation as well as methods to improve delivery of targeted radioimmunotherapy to tumor cells distant from the primary lesion, given the infiltrative nature of gliomas. The work to date with highly cytotoxic α-emitters and highly diffusible peptides is encouraging in this regard.